With six years of research experience in Europe's premier academicinstitute and8+ years of work experience in Indian Life science industry I have seen myself in varied roles as bench worker, core scientist, technical support, project manager, group leader, Incharge central instrumentation facility and Research Coordinator.
My passion for scientific research began during my post-graduate days wherein, I was introduced to the world of microorganisms and molecular biology and it continued by pursuing PhD in Universität Bremen, Germanywhere I learnt and gainedpersonal proficiency in many state-of–the art molecular techniques such as DNA & RNA Biology,Microarray technology (Antibody, Reverse Phase, DNA and RNA), big data analysis, Mammalian Cell culture systems, epigenetic studies,Invertebrate Identification, DNA Barcoding etc. After PhD I dived into experiencing the business scenario of Biotech industry in India by being part of a start-up bio services company managing genomics portfolio including contract research services, finishing school and in-house R&D. During this tenure, I was instrumental in getting the DSIR recognition for the start-up company.
At Vision Research Foundation as Principal Scientist and Research-coordinator I get to apply both my research expertise and scientific management experience. As researcher I am currently investigating the influence of genes in steroid response in the eye and I am also trying to perform Gene expression studies, DNA methylation studies and SNP analysis of ocular samples to understand vision threatening diseases.
As Research Coordinator I facilitate administrative meetings, Institutional Review Board meetings, multi institutional collaborations, engaging scientific community of the Institute with seminars, journal clubs, project discussion forums andworkshops on trending technologies.
My current research focus is Pharmacogenomics; unraveling the genetic predisposition for drug response in Indian population by applying Next generation sequencing technique leading to development of a diagnostic tool to screen drug responders vs non-responders.
Title: Genome wide association studies for Pharmacogenomics of steroid response in Eye
Funding Agency: Indian Council for Medical Research (ICMR) – Pharmacogenomics Taskforce (2017-present)
Summary: It is vastly known that the adverse secondary response to steroids leading to glaucoma in about 30% of population receiving intra vitreal injections is mainly because of Genetic predisposition. Single Nucleotide polymorphisms significantly altered in the responders may act as biomarkers to screen the patients before steroid administration so that alternative treatment modalities can be adapted by clinicians.
Google Scholar : Check out this link
2005 - 2008
Doctorate research fellowship from the European commission under the 6th Framework Programme for research.
Ms Lakshmi Badri
Senior Research Fellow
Ms Sanghmitra Rao
CSIR – Junior Research Fellow
Ms Maria Nancy Isaac
Vision Research Foundation
No. 41 (old 18), College Road,
Chennai - 600 006, Tamil Nadu , India.
Ph No: +91-44-42271500,
Fax No: +91-44-28254180